Possible Borderline Personality Disorder Causes

What Causes Borderline Personality Disorder (BPD)?

same woman showing different moods
What are the causes of borderline personality disorder?. Istockphoto.com/Stock Photo©KatarzynaBialasiewisz

The Possible Causes of Borderline Personality Disorder

If you or a loved one has borderline personality disorder (BPD), you may be wondering what caused it or if you are to blame. The development of this disorder is complex, and there are likely a variety of borderline personality disorder causes—and you should rest assured that no one person or thing is at fault. Most experts believe that BPD develops as a result of biological, genetic, and environmental factors.

However, it is important to keep in mind that the exact causes of BPD are not known yet. Right now, these are theories that have some support in support but are by no means conclusive. More research is needed to determine how and why the factors discussed below are related to BPD.

Potential Environmental Borderline Personality Disorder Causes

There is strong evidence to support a link between distressing childhood experiences, particularly involving caregivers, and BPD. The types of experiences that may be associated with BPD include:

  • Physical and sexual abuse
  • Early separation from caregivers
  • Emotional or physical neglect
  • Parental insensitivity

It is thought that an interaction between biological factors (discussed below) and an invalidating childhood environment may work together in predisposing a person to develop BPD. An emotionally invalidating environment is one in which a child's emotional needs are not met.

An invalidating environment is not always obvious to those who have experienced it or to others around them. These painful experiences can be hidden and even disguised as praise.

It is important to remember, however, that not everyone who has BPD has had these types of childhood experiences (although a large number have).

Further, even if a person does have these types of experiences, it does not mean that they will have BPD. Again, it is likely that a combination of factors, rather than a single cause, is responsible for most cases of borderline personality disorder.

Potential Genetic and Biological Borderline Personality Disorder Causes

While early studies showed that BPD does tend to run in families, for some time it was not known whether this was because of environmental influences or because of genetics. There is now some evidence that in addition to environment, genetic factors plays a significant role.

In particular, studies have shown that a variation in a gene which controls the way the brain uses serotonin (a natural chemical in the brain) may be related to BPD. It appears that individuals who have this specific variation of the serotonin gene may be more likely to develop BPD if they also experience difficult childhood events (for example, separation from supportive caregivers). One study found that monkeys with the serotonin gene variation developed symptoms that looked similar to BPD, but only when they were taken from their mothers and raised in less nurturing environments.

Monkeys with the gene variation who were raised by nurturing mothers were much less likely to develop BPD-like symptoms.

In addition, a number of studies have shown that people with BPD have differences in both the structure of their brain and in brain function. BPD has been associated with excessive activity in parts of the brain that control the experience and expression of emotion. For example, people with BPD have more activation of the limbic system, an area in the brain that controls fear, anger, and aggression, than people without BPD. This may be related to the emotional instability symptoms of BPD. Newer studies are also findings associated between the hormone oxytocin and the development of BPD.

Bottom Line on the Causes of Borderline Personality Disorder

As noted above, there is much to be learned about the causes of BPD and it's likely that it is a combination of factors rather than any one specific finding which can lead to the disorder. Research is in progress and hopefully we will learn more in the coming years.

Understanding the causes may help prevent the onset of disorder, especially in those who have a genetic or biological predisposition to the disorder. As it is, an invalidating environment is harmful for a child whether or not it raises the likelihood of BPD in the future, and it is important for therapists to be alert for this setting in children. Since an invalidating environment can be hidden, with many comments appearing to be comments of praise on the surface, emotions can easily be mistaken as an oversensitivity on the part of the child rather than a lack of sensitivity on the part of the parent. It's important for adults who experienced emotional invalidation as a child to learn to recognize the difference between validating and invalidating remarks from others to protect themselves from further hurt.

Sources:

Brune, M. On the Role of Oxytocin in Borderline Personality Disorder. British Journal of Clinical Psychology. 2016. 55(3):287-304.

Ruocco, A., and D. Carcone. A Neurobiological Model of Borderline Personality Disorder: Systematic and Integrative Review. Harvard Review of Psychiatry. 2016. 24(5):311-29.

Continue Reading