Can Resveratrol Lower Your Lipid Levels?


Resveratrol is a supplement that has been gaining a lot of popularity due to its positive health effects. This chemical is naturally found in many types of plants, as well as some common foods, including grapes, some nuts, and red wine. Resveratrol is also widely available as a supplement in various health food stores.

Components, including resveratrol, found in red wine have become heavily researched in recent years due to the decreased risk of cardiovascular disease noted in regions of the world where red wine is regularly consumed - such as France and Italy.

Studies have shown that resveratrol also has the ability to improve blood glucose levels, high blood pressure and can reduce inflammation. A few studies suggest that resveratrol may be able to help keep your lipid levels within a healthy range.

What Do the Studies Suggest?

There haven’t been many studies examining the effect of resveratrol on lipid levels – and the studies that do exist appear to have mixed results. There were very little participants in most of these studies, and the average dose of resveratrol taken in these studies was anywhere between 8 mg and 1500 mg a day over a period of 30 days and 6 months. In most cases, resveratrol was administered via a grape extract or in a lyophilized grape powder – both of which are high in resveratrol content. In some cases, resveratrol was administered alone or in a supplement that contained other heart-healthy ingredients, such as polyphenols or phytosterols.

Some studies appear to suggest that LDL levels may be lowered by anywhere between 3 and 20%, whereas triglyceride levels were lowered by up to 15%. On the other hand, other studies show no significant difference in LDL, HDL, or triglyceride levels in those taking some type of resveratrol supplementation.

It is not exactly known how resveratrol may work in lowering lipid levels. One study showed that resveratrol was able to lower cholesteryl ester transfer protein (CETP) by about 15%. CETP is a protein that transfers cholesteryl esters between lipoproteins and may contribute to high lipid levels if not functioning properly.

Should You Take Resveratrol to Lower Your Cholesterol?

There isn’t a lot of information available about resveratrol’s ability to lower lipid levels, but there is some evidence that resveratrol and resveratrol-containing foods may be cardioprotective and reduce inflammation. Until there is more research done in this area, resveratrol should not be used solely as an agent to lower your lipids. If you choose to take resveratrol for its other health benefits, you should talk to your healthcare provider first – or you can always gain this nutrient naturally from many types of foods, including:

  • Red grapes
  • Certain nuts, such as peanuts and walnuts
  • Blueberries


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Bhatt, J. K., Thomas, S., and Nanjan, M. J. Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus.Nutr.Res. 2012;32(7):537-541.

Tome-Carneiro, J., Gonzalvez, M., Larrosa, M., et al, Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial. Mol.Nutr Food Res 2012;56(5):810-821.

Poulsen MM, Vestergaard PF, Clasen BF et al. High-dose resveratrol supplementation in obese men an investigator-initiated, randomized placebo-controlled trial of substrate metabolism, insulin sensitivity, and body composition. Diabetes 2013; 62:1186-1195.

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