What Is the Clomid Success Rate for Ovulation and Pregnancy?

When Clomid Works Best and When It Doesn't

Woman showing pregnancy scan to male friend
Lilly Roadstones/Digital Vision/Getty Images

If you're considering Clomid, you likely want to know if it'll work for you. Will you ovulate? More importantly, will you get pregnant?

The good news is that the success rate for Clomid, in women with ovulatory problems, is pretty good. About 80% of women taking Clomid will ovulate during their first treatment cycle.

What about getting pregnant? The odds of conceiving in that first month is 30%. If 30% sounds low, keep in mind that a couple with no problems getting pregnant has about a 25% chance of getting pregnant in any given month.

But if you don't get pregnant after one month, don't panic. Needing more than one cycle is common. About 40 to 45% of couples get pregnant within six months of treatment.

Women are rarely treated with Clomid for more than six consecutive cycles.

When Is Clomid Not As Successful?

If there are additional problems besides irregular or absent ovulation, or there are any male factor infertility issues that have not been addressed, success will be lower.

It's questionable how successful Clomid therapy is for couples diagnosed with unexplained infertility.

Also, Clomid does not always work well in women who are dealing with age-related infertility, with low estrogen levels, or women with premature ovarian failure.

It may also not work in women whose ovulation problems are caused by a thyroid issue.

Women who are obese may have better success with Clomid if they lose weight.

What if you don't even ovulate while taking Clomid?

There are some things your doctor can try before suggesting other treatments.

If Clomid does help you ovulate, but after six months of treatment you still have not gotten pregnant, your doctor will help you look into alternative treatment options.

The next step may be a referral to a fertility clinic (if you're not already being seen at one), or your doctor may suggest gonadotropins (or injectable fertility drugs.)

More about Clomid:


Clomid Drug Information Sheet. Sanofi-Aventis. Accessed October 6, 2008. http://products.sanofi-aventis.us/clomid/clomid.pdf

Medications for Inducing Ovulation: A Guide for Patients. American Society of Reproductive Medicine. Accessed October 6, 2008. http://asrm.org/uploadedFiles/ASRM_Content/Resources/Patient_Resources/Fact_Sheets_and_Info_Booklets/ovulation_drugs.pdf

Continue Reading