Migraines and Headaches Treatment Could Prescriptions Make Your Headache Worse? Share Pin Email More in Migraines and Headaches Treatment Awareness Migraine Symptoms Diagnosis Coping Understanding Migraines Updated April 06, 2016 Prescriptions can worsen a headache. Here's what to watch out for. Up Next Up Next Video How to Cure a Headache Up Next Video Why Do You Get Headaches? Up Next Video Should You Seek Medical Attention for a Headache? Up Next Video What Are Primary Headaches?