Migraines and Headaches Treatment Could Prescriptions Make Your Headache Worse? Share Pin Email More in Migraines and Headaches Treatment Basics Migraine Symptoms Diagnosis Coping Understanding Migraines Updated April 21, 2016 Prescriptions can worsen a headache. Here's what to watch out for. Up Next Up Next Video Why Do You Get Headaches? Up Next Video Are There Prescriptions for Headaches? Up Next Video How to Cure a Headache Up Next Video Are Migraines Dangerous?