Links between Hepatitis and Fatigue: This Will Surprise You!

Fatigue Due to Hepatitis

Chronic fatigue is the most popularly reported indications of hepatitis infection. It affects 75 percent of patients diagnosed with hepatitis. It is important for you to know the factors that contribute to extreme sleep deprivation related to hepatitis and know the necessary steps you could take to manage fatigue.

Even if Western treatment has yet to discover the reason behind extreme tiredness related to hepatitis, several studies have shown many contributing factors.

  • Alcohol and drug use
  • Sleep deprivation and poor sleep
  • Depression and Stress
  • Other illness
  • Lack of work out
  • Chronic pain
  • Poor nutrition
  • Insufficient fluids and water
  • Damaged immune system
  • Specific medical treatments

Here are some factors that play significant role in Hepatitis related fatigue or tiredness:

Energy Storage

The function of the liver as related to energy production explains how HCV could lead to stress or tiredness. One of the major physiological tasks of the liver is: providing the body with a sufficient amount of energy. Apart from its renowned responsibility for sifting the blood, your liver also transforms foods into sugar for future use. Once the organs need energy, your liver generates stored sugar to give fuel for building energy. By storing, producing and supplying your body with sugar, your liver plays an essential role in preventing tiredness. A liver impervious to illness generates sugar between meals or every time your cells require energy and nourishment.

Interferon and Hepatitis

Though they’ve been the most preferred drug for curing hepatitis, interferons are also naturally-occurring materials that can cause stress. This medication is synthesized in order to match the immune system’s natural interferons. Portions of your security mechanism (your immune system) oppose infections.

These are proteins assisting your body in recognizing foreign molecules. This is believed to be the cause of flu and fatigue, which vanish once the medication is over.

Neurotransmitter-Related Immune Issues

Lasting response of the immune system to hepatitis gives the person a feeling of tiredness. The production of neurotransmitters is part of the healthy immune system reaction. Once your body is emotionally and physically stressed, your immune system activates. That in turn causes your brain to produce the right compounds for self-protection. Liver illness causes uncontrollable pressure, weakening the immune system as well as decreasing the production of specific neurotransmitters, which are chemical messengers used by organs.

Via research, experts found that specific kinds of liver injuries are related to immune reactions affecting the central nervous system. Experts also found that rats with a particular kind of liver illness had lessened levels of CRH, an important neurotransmitter for setting off fatigue.

Scientific investigators have discovered a defect in corticotrophin (a hormone) in people with long-term fatigue.

Handling Fatigue as a Hepatitis Patient

Stress and fatigue is an incredibly problematic sign of hepatitis. While specific lifestyle factors could lessen the effect of lethargy, a lot of people suffering from hepatitis should know how to handle stress. Being updated regarding the harmful effects of drug use, alcohol, dietary habits, poor sleep and highly demanding life could empower the person to make better changes in their lifestyle. Moreover, to make positive lifestyle options to lessen stress, these medications will also assist the liver as well as strengthen the immune system.

By stepping beyond the normal understanding of hepatitis, experts have teamed up with reliable nutritionists to devise a better approach to the issue of hepatitis-related fatigue. By means of assessing how to support the body in the release of energy on a cellular level, experts discovered that the mitochondria, which are parts of the cell that produce energy, work well if the membrane is completely intact.

Combining lots of nutritional components restores the membranes of mitochondria. While consumption of organic products for the restoration of energy should be conferred with a doctor, this efficient approach has assisted lots of hepatitis sufferers.  In addition to traditional positive lifestyle approaches, balancing everyday activities the right way could assist in managing tiredness. Helpful tips are listed below:

  • Try to prevent overloading your day with a hectic schedule by prioritizing necessities.
  • If possible, retain your energy by sitting down to do activities you normally do.
  • Pass on heavy, large meals in favor of frequent and smaller ones.
  • Pace yourself via regular breaks.
  • Take a warm (not hot) bath, as extreme temperatures can be very draining.
  • Develop a good sleep routine.

There’s been noted links between hepatitis and fatigue and many people have suffered from this condition. Reclaim your liveliness and energy by means of supporting your immune system and liver through positive lifestyle changes and having regular visits to your doctor. While the ability to get rid of hepatitis may be afar, you still have the capability, as a hepatitis patient, to conquer fatigue.


Poynard T, Cacoub P, Ratziu V, Myers RP, Dezailles MH, Mercadier A, Ghillani P, Charlotte F, Piette JC, Moussalli J. Fatigue in patients with chronic hepatitis C. J Viral Hepat. 2002 Jul;9(4):295-303.

Majer M, Welberg LA, Capuron L, Pagnoni G, Raison CL, Miller AH. IFN-alpha-induced motor slowing is associated with increased depression and fatigue in patients with chronic hepatitis C. Brain Behav Immun. 2008 Aug;22(6):870-80.

Jones EA. Fatigue complicating chronic liver disease. Metab Brain Dis. 2004 Dec;19(3-4):421-9.

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