How is Chlamydia Treated?

Close up image of woman holding a pill between her fingers just before placing it in her mouth
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Chlamydia is treated with antibiotics, and there are two recommended regimens for treatment. There are also several alternate regimens where those chlamydia treatments are inappropriate. Which treatment is most appropriate for you will depend on several factors. However, if you think you may have difficulty remembering to take a pill at the same time every day for 7 days, you should ask for a single dose treatment.

The single dose regimen may be slightly more expensive. However, extra expense will likely be offset by not needing to go in for a second round.

The two recommended treatment regimens are considered to be equally effective. The alternative regimens may be necessary for some individuals. Two of these alternates are more expensive (Ofloxacin/Levofloxacin) than the recommended treatment. The third (Erythromycin) may be less effective. This is because Erythromycin makes many people sick to their stomachs. That can affect the way the medication is absorbed.

When you are being treated for chlamydia it is important that your sexual partners are treated as well. If they are not, you could end up passing the infection back and forth between you. You should also abstain from sex for 7 days after the start of treatment. That will help keep you from infecting your sexual partners. If abstaining is not possible, make certain to use condoms for all sexual encounters – including oral sex.

The drug regimens below are taken from the Centers for Disease Control 2010 STD treatment guidelines. Remember that only your doctor can say which treatment is right for you.

Recommended ​Regim​ens for Non-Pregnant Adults

Azithromycin 1 g orally in a single dose
Doxycycline 100 mg orally twice a day for 7 days​

Alternative Regimens for Non-Pregnant Adults

Erythromycin base 500 mg orally four times a day for 7 days
Erythromycin ethylsuccinate 800 mg orally four times a day for 7 days
Ofloxacin 300 mg orally twice a day for 7 days
Levofloxacin 500 mg orally once daily for 7 days

Note: Pregnant women should not take doxycycline, ofloxacin, or levofloxacin. Azithromycin is considered to be both safe and effective. Follow-up is not recommended for non-pregnant patients with chlamydia because of the high efficacy of treatment. However, if you have been diagnosed with chlamydia during pregnancy, you should return to your doctor for a check-up 3 weeks after you’re done with treatment. That is because untreated chlamydia has potentially serious consequences for your pregnancy and your unborn child.

CDC (2010) "Sexually Transmitted Diseases Treatment Guidelines, 2010" Accessed (8/10/14) from

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