How Long Does Oxycontin Stay in Your System?

Detection Timetable Depends on Many Variables

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Avoiding an Oxy Overdose Is Critical. © Getty Images

How long oxycontin is detectable in the body depends on several factors, including which kind drug test is being used. Oxycontin - the brand name of oxycodone hydrochloride - can be detected for a shorter time with some tests, but can be "visible" for up to three months in other tests.

The timetable for detecting oxycontin in the system is also dependent upon each individual's metabolism, body mass, age, hydration level, physical activity, health conditions and other factors, making it almost impossible to determine an exact time oxycontin will show up on a drug test.

The following is an estimated range of times, or detection windows, during which oxycontin can be detected by various testing methods:

How Long Does Oxycontin Stay in the Urine?

Oxycontin can be detected in the urine for 3-4 days

How Long Can Oxycontin Be Detected in Blood?

A blood test can detect Oxycontin for up to 24 hours.

How Long Can a Saliva Test Detect Oxycontin?

A saliva test can detect Oxycontin for up to 1-4 days

How Long Can a Hair Test Detect Oxycontin?

Oxycontin, like many other drugs, can be detected with a hair follicle drug test for up to 90 days.

Avoiding an Oxycontin Overdose Is Critical

Oxycontin is prescribed to relieve moderate to severe pain and works by altering the way the brain and nervous system respond to pain. It is important to know just how long oxycontin remains in the system in order to avoid an accidental overdose. 

The following are some of the symptoms of an oxycontin overdose:

If you suspect someone has taken an overdose of oxycontin, call 9-1-1 immediately.

First-responders should be able to revive the victim with Narcan, but only if they are notified soon enough.

Other Dangers of Oxycontin

Even when using oxycontin as prescribed, it can cause serious or life-threatening breathing problems especially during the first three days that it is used.

Taking oxycontin with other medications can also life-threatening breathing problems. If a healthcare provider tries to administer or prescribe oxycontin to you, let them know of you are taking medication for any of the following:

  • Certain antibiotics
  • Certain antifungal medications
  • Medications for anxiety, mental illness or nausea
  • Muscle relaxants
  • Certain medications for HIV
  • Other narcotic pain medications
  • Sedatives
  • Sleeping pills
  • Tranquilizers

Drinking alcohol, or taking medications that contain alcohol, can also cause serious side effects when taking oxycontin.


Always Test Clean. "What Are Drug Detection Times?" Drug Test Facts Accessed December 2015

American Association for Clinical Chemistry "Drugs of Abuse Testing." Lab Tests Online. Revised 2 January 2013.

LabCorp, Inc. "Drugs of Abuse Reference Guide." Accessed March 2013.

OHS Health & Safety Services. "How long do drugs stay in your system?." Accessed March 2013.

U.S. National Library of Medicine. "Oxycodone." Drugs, Herbs, and Supplements. June 2015

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