How Long Does Tussionex Stay in Your System?

Detection Timetable Depends on Many Variables

Cough Syrup Bottle
How Long Does Tussionex Stay in the Boyd?. © Getty Images

Tussionex - a combination of chlorpheniramine and hydrocodone - can be detected for a shorter time with some tests, but can be "visible" for up to three months in other tests. Trying to estimate how long Tussionex is detectable in the body depends on many variables, including which kind drug test is being used.

The timetable for detecting Tussionex in the system is also dependent upon each individual's metabolism, body mass, age, hydration level, physical activity, health conditions and other factors, making it almost impossible to determine an exact time Tussionex will show up on a drug test.

The following is an estimated range of times, or detection windows, during which the hydrocodone ingredient in Tussionex can be detected by various testing methods:

How Long Does Tussionex Stay in the Urine?

Tussionex can be detected in the urine for 8-24 hours

How Long Can Tussionex Be Detected in Blood?

A blood test can identify Tussionex for up to 12 hours.

How Long Can a Saliva Test Detect Tussionex?

A saliva test can detect Tussionex for up to 1-2 days

How Long Can a Hair Test Detect Tussionex?

Tussionex, like like many other drugs, can be detected with a hair follicle drug test for up to 90 days.

Preventing a Tussionex Overdose?

Tussionex is a combination medication at contains chlorpheniramine, a antihistamine, and hydrocodone, an opiate analgesic pain reliever. It is mostly sold as a cough syrup to relieve the symptoms of allergies and colds.

It should be taken as directed to avoid possible side-effects and overdose.

Some symptoms of a Tussionex overdose include:

Call 9-1-1 immediately if you suspect someone is suffering from a Hydrocodone overdose. If caught early enough the overdose can be reversed with a treatment of Narcan.


American Association for Clinical Chemistry "Drugs of Abuse Testing." Lab Tests Online. Revised 2 January 2013.

LabCorp, Inc. "Drugs of Abuse Reference Guide." Accessed March 2013.

OHS Health & Safety Services. "How long do drugs stay in your system?." Accessed March 2013.

U.S. National Library of Medicine. "Hydrocodone." Drugs, Herbs and Supplements. May 2015

U.S. National Library of Medicine. "Chlorpheniramine." Drugs, Herbs and Supplements. May 2013

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