How Long Does Vicodin Stay in Your System?

Detection Timetable Depends on Many Variables

Man With Pills
Avoid a Vicodin Overdose. © Getty Images

Several factors are involved in determining exactly how long Vicodin is detectable in the body, including which kind drug test is being used. Vicodin - Hydrocodone bitartrate and acetaminophen - can be detected for a shorter time with some tests, but can be "visible" for up to three months in other tests.

The timetable for detecting Vicodin in the system is also dependent upon each individual's metabolism, body mass, age, hydration level, physical activity, health conditions and other factors, making it almost impossible to determine an exact time Vicodin will show up on a drug test.

The length of time that Vicodin remains detectable in the body also depends on how long someone has been taking the medication, how frequently and the amount of the dosage.

The following is an estimated range of times, or detection windows, during which Vicodin can be detected by various testing methods:

How Long Does Vicodin Stay in the Urine?

Vicodin can be detected in the urine for 3-4 days

How Long Can Vicodin Be Detected in Blood?

A blood test can detect Vicodin for up to 6-48 hours.

How Long Can a Saliva Test Detect Vicodin?

A saliva test can detect Vicodin for up to 3-4 days

How Long Can a Hair Test Detect Vicodin?

Vicodin, like many other drugs, can be detected with a hair follicle drug test for up to 90 days.

Prevent an Accidental Vicodin Overdose

Vicodin contains hydrocodone, an opiate analgesic, used to treat moderate to severe pain. Knowing how long it remains in the system can help prevent an accidental overdose by taking more of the medication too quickly.

The following are some of the symptoms that can occur with a Vicodin overdose:

If you suspect someone is suffering from a Vicodin overdose, call 9-1-1 immediately. If caught early enough, the overdose can be reversed with a treatment of Narcan.


Always Test Clean. "What Are Drug Detection Times?" Drug Test Facts Accessed December 2015

American Association for Clinical Chemistry "Drugs of Abuse Testing." Lab Tests Online. Revised 2 January 2013.

LabCorp, Inc. "Drugs of Abuse Reference Guide." Accessed March 2013.

OHS Health & Safety Services. "How long do drugs stay in your system?." Accessed March 2013.

National Institue on Drug Abuse. "Hydrocodone/oxycodone overdose." Drugs, Herbs and Supplements November 2010

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