The Avent Isis is my favorite choice of manual pump. The suction level and silicone insert are comfortable and it only takes one hand to operate. The Isis is also inexpensive and is compatible with the entire line of Avent bottles and tops. Occasionally, I had problems achieving let-down, but luckily it&#39;s smooth and easy to operate so my hand didn&#39;t get tired when I had to pump a little longer before the reflex kicked in.The Pedal Pump is more expensive than other manual pumps, but worth it. This is the only manual pump I would recommend for mothers who pump more than just occasionally. Because it uses the power of your foot, it&#39;s much easier to pump longer. You can get a better quantity of milk and can more effectively build your milk supply without tiring out your arms or hands. An added bonus: You can pump both breasts at the same time, unlike most manual pumps.The Harmony pump is comparable to the Avent Isis, with a soft insert that is very comfortable and with its one-handed use design. It also has multiple modes that imitate the way your baby nurses, which is helpful in stimulating the let-down reflex. It also has fewer parts than other pumps, which really helps if you need to clean the pump more than just occasionally. If you&#39;re using a traditional bottle system as opposed to the Avent system, this is the pump for you.This pump makes the list mainly because of its size. It is so compact, you can fit it in your purse, a desk drawer, the glove compartment or just about anywhere you might want. It has a one-hand use design like some other pumps, but it uses a slightly different grip that might make it a little less comfortable to operate for some moms.