Why the Anatomy of the Coronary Arteries Matters

coronary arteries
Right and coronary arteries. SCIEPRO/Getty Images

The coronary arteries are the blood vessels that supply blood to the myocardium (heart muscle). Because it must work continuously (as opposed to other muscles of the body, which are often at rest), heart muscle has a very high requirement for oxygen and nutrients, and therefore requires a very reliable, continuous supply of blood. The coronary arteries are designed to deliver the continuous blood supply necessary for the heart to work properly.

If the blood flow through the coronary arteries become partially blocked, the heart muscle may become ischemic (oxygen starved), a condition that often produces angina and a drop-off in muscle function (manifested by weakness and dyspnea). If the blood flow becomes completely blocked, the heart muscle supplied by the blocked artery can suffer infarction, or cell death. This is called a myocardial infarction, or heart attack.

Why The Anatomy Of The Coronary Arteries Matters

The two major coronary arteries, the right coronary artery (RC) and the left main (LM) coronary artery, arise from the aorta (the body’s main artery) just beyond the heart’s aortic valve.

The LM artery quickly branches into two large arteries – - the left anterior descending artery (LAD) and the circumflex artery (Cx). The heart muscle itself, then, is supplied by one of these three major coronary arteries: the LAD, the Cx, and the RC.

The picture (above) shows the RC and the LAD arteries. (The Cx artery is depicted by a ghost-like shadow behind the heart.)

The RC artery is shown on the left side of the figure, coursing around the edge of the heart. The long segment of the RC that, in this picture, goes to the very tip of the heart (the apex) is called the posterior descending artery (PDA).

In most people (about 75%) the PDA comes off the RC, as in this picture. This is called “right dominant.” However, in 25% the PDA arises from the Cx artery, which is called “left dominant.” This distinction is important, since (for instance) a heart attack arising from blockage in the RC in a right dominant heart will do more damage than it would in a left dominant heart.

The RC artery and its branches supply blood to most of the right atrium, right ventricle, sinus node, and (in most people) the AV node.

Returning to the picture, the LAD and its many branches are shown coursing down toward the apex from the top of the heart. The LAD supplies the left atrium and major portions of the left ventricle - the heart’s major pumping chamber. So a heart attack arising from blockage in the LAD almost always does serious damage. Coronary artery plaques in the LAD are often referred to by cardiologists as “widow makers.”

The significance of the damage done to the heart muscle during a heart attack depends not only on which artery is affected, but also on the location of the blockage within the artery.

A blockage close to the take-off of the artery will likely do far more damage than a blockage further down the artery, or in one of its small branches. If a heart attack occurs, permanent damage can often be prevented by getting immediate medical attention, as several strategies are available for quickly opening a blocked coronary artery.


Farooq V, van Klaveren D, Steyerberg EW, et al. Anatomical and clinical characteristics to guide decision making between coronary artery bypass surgery and percutaneous coronary intervention for individual patients: development and validation of SYNTAX score II. Lancet 2013; 381:639.

Authors/Task Force members, Windecker S, Kolh P, et al. 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J 2014; 35:2541.


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