Should You Stop Medications That Lower Your Cholesterol?

What Would Happen if You Stopped Your Cholesterol-Lowering Drugs?

Lipitor is a cholesterol-lowering drug.
Lipitor is a cholesterol-lowering drug. Scott Olson/Getty Images

If you stop medications to lower your cholesterol, does that hurt you? Cholesterol-lowering drugs benefits and side effects. Perhaps you have been taking cholesterol medication for a year or longer. Your doctor says your blood levels are perfect. You feel fine. Is staying on your drug regimen really necessary?

Even with a perfect diet and regular exercise, many people still require medication to keep cholesterol levels in check and prevent the risk of heart attack or stroke.

Once the medication is stopped, cholesterol may return to unhealthy levels, raising the risk of developing coronary heart disease.

As many as 70% of individuals with high cholesterol have a genetic predisposition to the heart disease, even if they do not have other related risk factors. These individuals may never be able to get their cholesterol to a healthy level without medication, even with a low-fat diet and regular physical activity. Standard blood tests are the first level of screening for this form of high cholesterol.

Temptations to Stop Your Cholesterol-Lowering Drugs

Individuals sometimes develop unpleasant side effects when taking cholesterol medication, such as severe blushing or muscle cramps. If this happens, contact your healthcare provider right away, as these side effects occasionally signal a potentially dangerous condition. In most cases, switching to a different medication, or changing the way you take the one you're on, can reduce or eliminate side effects.

Medication expense can be another deterrent. Often, individuals who take cholesterol medication are also taking several other pills on a daily basis to manage conditions such as high blood pressure or diabetes. The cost of multiple medications can quickly add up, tempting some individuals to stop taking prescriptions that seem less important.

Again, talk to your doctor. In many cases, generic medications, which are generally much cheaper, can be prescribed.

Even individuals with the best intentions can get tired of taking multiple medications year after year. Others may wish to switch from prescription drugs to more natural remedies, such as fiber supplements. While alternative remedies are not well studied, some may be reasonable choices for some patients. If you're interested in one of these options, or if you're contemplating stopping or changing your medication, be sure to speak with your doctor first.

The Benefits of Continuing Your Cholesterol Medications

Some conditions simply cannot be managed effectively without a prescription. If you have diligently managed to lower your cholesterol levels, but then choose to stop taking your medicine, all those years of hard work may be effectively erased. If your cholesterol levels creep back up, you will once again be at higher risk of developing a heart attack or stroke, just as though you had never even taken any cholesterol medication. Cholesterol levels must stay low to protect against heart disease.

Even if cholesterol levels are already normal, statin medications -- which inhibit the production of cholesterol in the liver -- decrease the risk of heart attack or stroke for people with other risk factors, such as high blood pressure or a prior heart attack or stroke.

In addition to lowering cholesterol levels, statins also help to make plaque deposits more fibrous and less fatty. This stabilizes plaques so that they are less likely to break off from arterial walls and travel through the bloodstream, where they can cause a blockage in the heart or brain that can result in a heart attack or stroke. Although herbal or natural remedies might lower cholesterol, they may not provide the same level of protection against heart attack or stroke as prescription statin medications.

If you consistently take your cholesterol medication daily and your cholesterol levels are low, keep up your good work.

Know that you are taking good care of your body. More importantly, if you have questions about your medications, be sure to ask your doctor. Doing so will help you develop a good understanding of exactly why each prescription is important for you.


Furie, Karen L., Janet L. Wilterdink, and J. Philip Kistler. "Secondary Prevention of Stroke: Risk Factor Reduction." 2008. UpToDate. 24 Mar. 2008. (subscription).

Genest, J.J., et. al.. "Familial Lipoprotein Disorders in Patients with Premature Coronary Artery Disease." Circulation. 85. Jun. 1992. 2025-2033.

Hennekens, Charles H. "Primary Prevention of Coronary Heart Disease and Stroke." 2008. UpToDate. 30 Mar. 2008.

Rosenson, Robert S. "Overview of Treatment of Hypercholesterolemia." 2008. UpToDate. 30 Mar. 2008.

Sever, P.S., et al. "Prevention of Coronary and Stroke Events With Atorvastatin in Hypertensive Patients Who Have Average or Lower-Than-Average Cholesterol Concentrations, in The Anglo-Scandinavian Cardiac Outcomes Trial - Lipid Lowering Arm (ASCOT-LLA): A Multicentre Randomised Controlled Trial." Drugs. 64. (2004). 43-60.

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