Can Shoulder Pain Be a Symptom of Lung Cancer?

When Might Shoulder Pain Be a Sign of Lung Cancer?

woman touching her painful shoulder
Can shoulder pain be a symptom of lung cancer?. Tetra Images/Brand X Pictures/Getty Images

Can Shoulder Pain Be a Symptom of Lung Cancer?

Yes, shoulder pain can indeed be a symptom of lung cancer. In fact, shoulder pain is sometimes the first symptom of lung cancer.

Many people with lung cancer develop shoulder pain during the course of their disease. That said, it's important to note that shoulder pain is not a lung cancer telltale. In addition, in patients with lung cancer, the shoulder pain may be the result of their disease or instead, due to another cause such as arthritis.

Why Can Lung Cancer Cause Shoulder Pain?

Lung cancer-related shoulder pain can be caused by a number of different mechanisms:

Pain in your shoulder could be referred pain (meaning that the pain is felt in the shoulder but originates somewhere else) that is due to pressure from a tumor on the phrenic nerve within the lungs. In this case, the brain interprets pain as coming from the shoulder, when in fact, the nerve is being irritated within the lungs.

Shoulder pain in lung cancer can also be related to the spread of lung cancer to bones in and near the shoulder. Roughly 30 percent to 40 percent of people with lung cancer develop bone metastases (the spread of cancer to bones) at some time during their disease.

Pancoast tumors, a form of lung cancer, grow near the upper part of the lungs and can invade tissues near the shoulder. Pancoast tumors often cause pain in the shoulder that radiates down the arm.

Due to their location, these tumors are less likely to cause typical symptoms of lung cancer such as a persistent cough, coughing up blood and shortness of breath.

Malignant pleural mesothelioma is a cancer of the pleura - the membranes lining the lungs - and is most commonly caused by exposure to asbestos on the job.

In one study it was found that 14 percent of patients developed shoulder pain as their first symptom of mesothelioma. If you have worked in construction or done a home remodeling project, make sure to let your doctor know.

How Is Shoulder Pain Due to Lung Cancer Different From Other Causes of Shoulder Pain?

Unfortunately,shoulder pain related to lung cancer can be very similar to that of conditions such as arthritis. Symptoms that may be more concerning, however, include shoulder pain that is worse at night, pain that occurs at rest, and pain that is not associated with any loss of motion with activity.

Shoulder pain is also more likely to be a symptom of lung cancer if you have other symptoms of lung cancer, such as shortness of breath (this can be mild and only with activity,) a persistent cough (even if it is only intermittent) or if you are losing weight for no reason.

Keep in mind that the symptoms of lung cancer in women and symptoms of lung cancer in non-smokers are often less typical than those in men - and sometimes very vague, such as shortness of breath with activity and fatigue.

Treatment of Shoulder Pain Due to Lung Cancer

Treatment of shoulder pain related to lung cancer can depend on the underlying cause. If the pain is referred pain from pressure on a nerve in the lung, treatment that decreases the tumor within the lungs is the primary goal. If a tumor is growing near the top of the lungs, surgery to remove the tumor or treating the tumor with radiation may relieve symptoms. If the pain is related to bone metastases, treatment with radiation therapy may reduce symptoms significantly.


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