Strong Suppression of Hepatitis Antibodies

Suppression of Hepatitis Antibodies

Hepatitis is becoming more and more of a mortality threat to many across the globe. With this at hand, a lot of research and experiments have been accomplished in order to discover ground-breaking medical treatments for this dangerous liver disease. Following years of testing, it’s been found out that there are a number of ways by which this condition can be tamed. Among these are changes in one’s lifestyle, and the application of different herbal medications.

Through more studies, however, there has been a discovery of the aggressive suppression of hepatitis antibodies themselves.

Hepatitis and Antibodies Deciphered

Simply put, the human body has the natural ability to heal itself. This is due to the presence of various enzymes and bodily substances, which are innate within the body system. Whenever our cells feel that a foreign body is attacking or invading, they immediately release substances in a scrambled protective effort. These materials are collectively called antibodies. Because of these, each organ has the aptitude of protecting itself from a myriad of risks. This is why, to a certain extent, people can still recover from hepatitis in the absence of medication.

Although the body has this capability, the slackened rate at which your body heals itself is often not speedy enough for more serious sicknesses. One such sickness is hepatitis, or when the liver suffers from inflammation.

In response to this, different medicines have been developed and are meant to be taken for certain illnesses. Unfortunately, some patients are unaware that a range of medicines may inflict further damage rather than cure certain regions of the body. Some synthetic drugs actually supress the antibodies in the organ.

One of these organs is the liver--and this is something that hepatitis sufferers ought to make a note of. This means that the more you consume these drugs, the greater the inhibition of your antibodies. That in turn may mean even dawdle self-healing. Now the following question arises: does this kind of medication really have benefits or are there actually just added disadvantages?

Antibodies for Hepatitis Patients

To obtain a valid response to the question above, we need to have an understanding about a specific antibody found in the liver, called human leukocyte antigen (HLA) antibodies. This substance is mainly found on the hepatocytes’ (liver cells’) surface. These are the cells that toil around all day in the major tissues of the said organ. The functions (either direct or indirect) of HLA antibodies include the following:

  • Protein synthesis and storage assistance
  • Phospholipids, cholesterol, and bile salt breakdown
  • Conversion of carbohydrates
  • Modification, detoxification, as well as excretion of endogenous and exogenous substances
  • Commencement of bile formation and its subsequent secretion

This natural liver substance (HLA) is manufactured in light of the normal synthesizing functions of the liver. However, there are instances when abnormalities take place. Sometimes, foreign matter isn’t the most obvious reason the liver gets infected. In some instances, antibodies (which normally protect the liver) turn on the liver itself, as if they’re assuming the role of antigens instead. As a result, this unusual response leads to the inflammation of the organ, or autoimmune hepatitis, which can further develop to hepatic cirrhosis.

Reasons for Suppressing Antibodies

Due to this abnormality, steps have been made to somehow regulate the production of leukocyte antigen and other antibodies in the liver. The method is still questionable for many health advocates. To them, this medical principle isn’t acceptable because the human body already possesses powerful natural processes. Suppression of these antibodies in that regard would only mean reducing the strength of the organ to protect itself against pathogens.

Aside from the leukocyte antigen, other antibodies include the nine anti-mitochondrial antibodies (M1-M9). They generally function as “built-in doctors” of the liver. Upon ingestion of medicines, especially synthetic drugs, these antibodies are disturbed. When a person becomes increasingly dependent on them, he fuels the chances of killing these anti-pathogen antibodies.

The problem is that antibodies don't always instantaneously accept the new organ, so they may have to be suppressed using certain immunosuppressive drugs. One of the drawbacks of this procedure is “immunodeficiency.” Once someone has this condition, the immune system becomes less adept at fighting health-threatening substances that enter the body. This increases the hepatitis patient’s proneness to a score of infections. Even the body’s cancer immune-surveillance is weakened. Though a patient thinks that his liver function is boosted upon receiving shots of medicines, things are actually the other way around. In point of fact, the organ may become weaker.


Franceschini N, Napravnik S, Finn WF, Szczech LA, Eron JJ Jr. Immunosuppression, hepatitis C infection, and acute renal failure in HIV-infected patients. J Acquir Immune Defic Syndr. 2006 Jul;42(3):368-72.

Wong DK, Watanabe T, Tanaka Y, Seto WK, Lee CK, Fung J, Lin CK, Huang FY, Lai CL, Yuen MF. Role of HLA-DP polymorphisms on chronicity and disease activity of hepatitis B infection in Southern Chinese. PLoS One. 2013 Jun 25;8(6):e66920.

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