Synbiotics: Studies Reveal Women Lose More Fat than Men

Synbiotics Linked to Reduced Body Mass Index (BMI)

Current studies are looking at synbiotics as a way to achieve sustainable weight loss and although research is in early stages, the feedback is promising.  Synbiotics are a combination of probiotics and prebiotics supplemented for the purpose of reducing gut bacteria linked to increased fat.  Since the discovery of certain gut microbes having a link to obesity, and successfully changing colon environment to create a “lean” shift, science has continued to dig deeper into sustainable weight loss through feeding the gut “good bacteria” with synbiotics.  Published recently by the British Journal of Nutrition, “LPR-induced weight loss in women was associated not only with significant reductions in fat mass and circulating leptin concentrations but also with the relative abundance of bacteria of the Lachnospiraceae family in faeces.”  Science is simply saying women who took the synbiotic supplement during testing lost lots of fat and increased the good bacteria in their colon showing a positive result with the research.   

Synbiotics Decrease Body Mass Index (BMI)

Women Lose More Fat Using Synbiotics. Mike Harrington

 Another study by the National Institutes of Health reported “One month of supplementation of the synbiotic resulted in a significant reduction of weight and body mass index. “ The research is more credible when conducted on humans vs. animals and typically rats.  Although great information from animal studies, their physiological makeup is different than ours and results would be purely speculation of similar responses in humans.  The British Journal of Nutrition research revealed synbiotics to be helpful for both men and women during the 24-week randomized trial but made note of a new discovery for women showing greater results.  In fact, during the maintenance phase of testing, women in the synbiotic group continued to lose body weight and fat mass while increasing their good gut bacteria.    

Synbiotics: Women More Responsive

Synbiotics and Fat Loss
Synbiotics Reveal Women More Responsive to Supplementation. Brand New Images DigitalVision/Getty Images

 The hypothesis of the study was meant to prove synbiotics as a useful approach to weight loss management for both obese men and women and having stumbled across the gender specific results of women responding at a higher level will require further testing.  As stated by Dairy and Food Culture Technologies, “The observation that women were more responsive than men to the synbiotic instead leads to a hypothesis for a follow-up study, designed for this endpoint.”  The research thus far is respectable with regards to prebiotics, probiotics and now synbiotics role in improving bad gut bacteria and links to weight loss management. 

Gut Bacteria Influences Being Fat or Thin

Gut Bacteria Fat or Thin
Gut Bacteria Can Influence Being Fat or Thin. SEBASTIAN KAULITZKI Science Photo Library/Getty Images

 Gut bacteria has become a current and trending topic of medical discussion and research.  The recent discoveries of “bad bacteria” and links to obesity have supercharged research to swing the scales in the direction of “good bacteria” living in the gut to stimulate less fat in the human body.  It appears synbiotics are making a positive appearance as a possibility to achieve sustainable weight loss, reduce body mass index (BMI), and improve overall health especially for women.  Making sure our gut is abundant in “good bacteria” is an important part of being healthy and if supplementing with synbiotics (probiotic + prebiotic) will enhance our intestinal flora, it may be a great idea to have a discussion with your doctor to see if it is right for you.  Read more about the subject of gut bacteria and how it influences our being fat or thin.  

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Bonus: Eat to Build Good Bacteria

Ready, set, chop!
Eat Healthy to Build Good Gut Bacteria. Peopleimages / Getty Images

Nothing replaces eating right and exercise as the main contributors for a healthy body.  It's exciting to read about new discoveries to help achieve those goals. Gut bacteria is being reported as a major player in overall health. Making sure the "good" stuff is abundant in our colons will come from the foods we eat.  As science continues to research improving good gut bacteria, ensure your nutrition includes a wide variety of healthy foods to fight off "bad bacteria".  I hope this article was informative and helpful on your journey to health and fitness. 


Beneficial Microbes, Effects of synbiotic on anthropometry, lipid profile and oxidative stress in obese children, Ipar N et al., 8/15

California Dairy Research Foundation, Synbiotics and Weight Loss, Mary Ellen Sanders , Dairy & Food Culture Technologies, 2/14

British Journal of Nutrition, Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women, Sanchez M et al., 4/28/14

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