The Benefits of Cetyl Myristoleate

Health Benefits, Uses, Tips, and More

Cetyl myristoleate is a fatty acid sold in dietary supplement form. Said to reduce inflammation, cetyl myristoleate is touted as a natural treatment for a number of health conditions.

Uses for Cetyl Myristoleate

In alternative medicine, cetyl myristoleate is said to help with the following health problems:

In treatment of arthritis, cetyl myristoleate is either taken in supplement form or applied directly to the skin (typically in the form of a cream).

Cetyl myristoleate is also said to boost the immune system.

Health Benefits of Cetyl Myristoleate

Although research on the health effects of cetyl myristoleate is limited, some studies show that it may aid in the treatment of osteoarthritis.

In a 2004 study published in the Journal of Rheumatology, for example, researchers found that use of a cream containing cetyl myristoleate helped improve functioning in people with osteoarthritis of the knee. For the study, 40 patients with osteoarthritis of the knee were randomly assigned to one of two treatments: a cream made with cetyl myristoleate, or a placebo cream. After 30 days of twice-daily treatment, those given cetyl myristoleate showed greater improvements in range of motion in their knees (as well as in balance, ability to ascend/descend stairs, and ability to rise from sitting).

Additionally, a 2002 study from the same journal found that consuming cetyl myristoleate in supplement form may help improve knee range of motion and overall function in patients with osteoarthritis of the knee. The study involved 64 patients with osteoarthritis of the knee, each of whom was treated with either cetyl myristoleate or a placebo for 68 days.

Compared to members of the placebo group, those treated with cetyl myristoleate showed greater functional improvements by the study's end.

In tests on animals, scientists have determined that cetyl myristoleate may help treat arthritis by reducing inflammation.


Due to a lack of research, little is known about the safety of long-term or regular use of cetyl myristoleate.

Keep in mind that supplements haven't been tested for safety and dietary supplements are largely unregulated. In some cases, the product may deliver doses that differ from the specified amount for each herb. In other cases, the product may be contaminated with other substances such as metals. Also, the safety of supplements in pregnant women, nursing mothers, children, and those with medical conditions or who are taking medications has not been established. You can get further tips on using supplements here.

Alternatives to Cetyl Myristoleate

A number of other natural remedies may help alleviate arthritis symptoms. For example, some studies show that increasing your intake of omega-3 fatty acids may help treat arthritis.

There's also some evidence that dietary supplements like glucosamine, chondroitin sulfate, and avocado/soybean unsaponifiables may aid in arthritis management.

In addition, practicing yoga, taking up tai chi, and/or undergoing acupuncture may help curb arthritis pain and improve functioning.

Where To Find It

Widely available for purchase online, cetyl myristoleate is sold in some natural-foods stores, drugstores, and stores specializing in dietary supplements.

Using Cetyl Myristoleate for Health

Due to the limited research, it's too soon to recommend cetyl myristoleate as a treatment for any condition. It should be noted that self-treating a condition with cetyl myristoleate and avoiding or delaying standard care may have serious consequences. If you're considering using it, make sure to consult your primary care provider first.


Ameye LG, Chee WS. "Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence." Arthritis Res Ther. 2006;8(4):R127.

Diehl HW, May EL. "Cetyl myristoleate isolated from Swiss albino mice: an apparent protective agent against adjuvant arthritis in rats." J Pharm Sci. 1994 Mar;83(3):296-9.

Hesslink R Jr, Armstrong D 3rd, Nagendran MV, Sreevatsan S, Barathur R. "Cetylated fatty acids improve knee function in patients with osteoarthritis." J Rheumatol. 2002 Aug;29(8):1708-12.

Hunter KW Jr, Gault RA, Stehouwer JS, Tam-Chang SW. "Synthesis of cetyl myristoleate and evaluation of its therapeutic efficacy in a murine model of collagen-induced arthritis." Pharmacol Res. 2003 Jan;47(1):43-7.

Kraemer WJ, Ratamess NA, Anderson JM, Maresh CM, Tiberio DP, Joyce ME, Messinger BN, French DN, Rubin MR, Gómez AL, Volek JS, Hesslink R Jr. "Effect of a cetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis." J Rheumatol. 2004 Apr;31(4):767-74.

Disclaimer: The information contained on this site is intended for educational purposes only and is not a substitute for advice, diagnosis or treatment by a licensed physician. It is not meant to cover all possible precautions, drug interactions, circumstances or adverse effects. You should seek prompt medical care for any health issues and consult your doctor before using alternative medicine or making a change to your regimen.

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