The Benefits and Uses of Malic Acid

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Malic acid is a substance found naturally in apples and pears. It's considered an alpha-hydroxy acid, a class of natural acids commonly used in skin-care products. Also sold in dietary supplement form, malic acid is said to offer a variety of benefits.

Uses for Malic Acid

When applied to skin, malic acid is said to reduce signs of aging (including wrinkles), remove dead skin cells, aid in the treatment of acne, and promote skin hydration.

Malic acid is also used to improve sports performance when taken in supplement form. It is often combined with creatine in order to improve the absorption of creatine. Proponents claim that malic acid can energy production, boost endurance during exercise, and help fight off muscle fatigue.

In addition, consuming malic acid in combination with magnesium is sometimes said to alleviate symptoms of fibromyalgia (including pain).

The Skin-Care Benefits of Malic Acid

A number of early studies published in the 1990s and early 2000s indicate that malic acid may be beneficial when applied to the skin. In tests on animals and human cells, the studies' authors found that malic acid may help increase collagen production and reverse sun-induced signs of aging in the skin.

More recent research on topically applied malic acid includes a small study published in the Journal of Drugs in Dermatology in 2013.

For the study, researchers assigned 35 people with melasma (a common disorder marked by patches of abnormally dark skin) to a skin-care regimen that included the use of topically applied vitamin C and malic acid. At an average follow-up of 26 months, the regimen was found to be an effective short-term treatment for melasma.

The Benefits of Malic Acid Supplements

To date, few studies have tested the health effects of taking malic acid in supplement form. However, there's some evidence that malic acid may offer certain benefits when ingested.

Kidney Stones
Malic acid is a precursor to citrate, a substance believed to prevent calcium from binding with other substances in urine that form kidney stones. Citrate may also prevent crystals from getting bigger by preventing them from sticking together. In a 2016 review, scientists suggest that studies evaluate whether a diet supplemented with pears and associated with low meat and salt intake may reduce stone intake.

According to a preliminary laboratory study published in 2014, malic acid consumption may make urine less favorable for the formation of stones, by increasing the pH of urine and increasing urinary citrate levels. The study authors conclude that malic acid supplementation may be useful for the conservative treatment of calcium kidney stones.

Physical Performance

For a study published in Acta Physiologica Hungarica in 2015, researchers investigated the effectiveness of a creatine-malate supplement in sprinters and long-distance runners. After six weeks of supplementation combined with physical training, a significant increase in physical performance (measured by peak power and total work, body composition changes, and elevated growth hormone levels) was found in sprinters.

In long-distance runners, there was a significant increase in distance covered.

Dry Mouth

The use of a 1 percent oral malic acid spray has been explored as a treatment for dry mouth. A study published in Depression and Anxiety, for instance, evaluated a 1 percent malic acid spray compared to a placebo in people with dry mouth resulting from antidepressant use. After two weeks of using the sprays as needed, those using the malic acid spray had improved dry mouth symptoms and increased saliva flow rates.


A small pilot study published in the Journal of Rheumatology in 1995 found that taking malic acid in combination with magnesium helped alleviate pain and tenderness in people with fibromyalgia.

For the study, researchers assigned 24 fibromyalgia patients to treatment with either a placebo or a combination of malic acid and magnesium. After six months, those treated with the malic acid/magnesium combination showed a significant improvement in pain and tenderness. However, there's a lack of recent research on malic acid's effectiveness as a fibromyalgia treatment.

Possible Side Effects

Due to a lack of research, little is known about the safety of long-term or regular use of malic acid supplements. However, there's some concern that intake of malic acid may trigger certain side effects such as headaches, diarrhea, nausea, and allergic reactions.

Although malic acid is generally considered safe when applied to the skin in the recommended amount, some people may experience irritation, itching, redness, and other side effects. It's a good idea to patch test new products.

In addition, alpha-hydroxy acids are known to increase your skin's sensitivity to sunlight. Therefore, it's important to use sunscreen in combination with skin-care products containing any type of alpha-hydroxy acid.

Keep in mind that malic acid shouldn't be used as a substitute for standard care. Self-treating a condition and avoiding or delaying standard care may have serious consequences.

You can get additional tips on using supplements here, but if you're pregnant or nursing, are taking medication or supplements, or have a health condition (such as heart or kidney disease), it's particularly important that you talk with your doctor before taking any new supplement. 

The Bottom Line

Malic acid is found in fruits and vegetables and is produced naturally in the body when carbohydrates are converted into energy. Using malic acid as part of your skin care routine may help with concerns such as pigmentation, acne, or skin aging. But keep in mind that it's a good idea to patch test when using new products and to avoid the eye area.

While some research suggests that malic acid supplements may help people with certain conditions, high-quality clinical trials are needed. If you're still considering using it, consult your doctor before taking it to discuss the potential risks and benefits. 


Gómez-Moreno G, Aguilar-Salvatierra A, Guardia J, et al. The efficacy of a topical sialogogue spray containing 1% malic acid in patients with antidepressant-induced dry mouth: a double-blind, randomized clinical trial. Depress Anxiety. 2013 Feb;30(2):137-42.

Rodgers AL, Webber D, de Charmoy R, Jackson GE, Ravenscroft N. Malic acid supplementation increases urinary citrate excretion and urinary pH: implications for the potential treatment of calcium oxalate stone disease. J Endourol. 2014 Feb;28(2):229-36.

Taylor MB, Yanaki JS, Draper DO, Shurtz JC, Coglianese M. Successful short-term and long-term treatment of melasma and postinflammatory hyperpigmentation using vitamin C with a full-face iontophoresis mask and a mandelic/malic acid skin care regimen. J Drugs Dermatol. 2013 Jan;12(1):45-50.

Tyka AK, Chwastowski M, Cison T, et al. Effect of creatine malate supplementation on physical performance, body composition and selected hormone levels in spinters and long-distance runners. Acta Physiol Hung. 2015 Mar;102(1):114-22.

Disclaimer: The information contained on this site is intended for educational purposes only and is not a substitute for advice, diagnosis or treatment by a licensed physician. It is not meant to cover all possible precautions, drug interactions, circumstances or adverse effects. You should seek prompt medical care for any health issues and consult your doctor before using alternative medicine or making a change to your regimen.