Thyroid Drugs and Manufacturers Information / Websites

Updated November 2015

drug companies, drugs, thyroid drugs
Malcolm Park, Stockbyte

THYROID REPLACEMENT DRUGS

Thyroid hormone replacement drugs are drugs used to treat hypothyroidism. They help to resolve hypothyroidism by replacing missing hormone. 

LEVOTHYROXINE

  • Levothyroxine is a synthetic version of the thyroid hormone thyroxine, known as T4. Levothyroxine is sometimes called "l-thyroxine" or "L-T4."
  • Primary brand names of levothyroxine: Synthroid, Levoxyl, Unithroid, Tirosint, also generics made by various companies

    LIOTHYRONINE

    • Liothyronine is a synthetic version of the thyroid hormone triiodothyronine, known as T3.
    • Only brandname liothyronine is Cytomel, generics are also available

    NATURAL DESICCATED THYROID

    • Natural Desiccated Thyroid -- abbreviated as NDT -- is a prescription medication made from the desiccated (dried) thyroid glands of pigs.
    • Also known as "porcine thyroid," "natural thyroid," and "pig thyroid."
    • FDA-regulated prescription drug, includes natural forms of T4, T3, as well as T1, T2
    • Key brands are Armour Thyroid, owned by Actavis/Allergan (formerly Forest Pharmaceuticals), Also Nature-throid and WP Thyroid from RLC, and a generic in the US (Thyroid NP) made by Acella

    COMPOUNDED THYROID MEDICATIONS

    • Compounding pharmacies can compound time-released or regular T3, and create combinations of levothyroxine/natural thyroid, by prescription

    DISCONTINUED

    • Thyroid medications that have been discontinued and no longer available include Thyrolar (generic name, liotrix, a synthetic T4/T3 combination), and the Levothroid brand of levothyroxine
       

      ANTITHYROID DRUGS

      Antithyroid drugs are used to treat an overactive thyroid - hyperthyroidism.

      METHIMAZOLE (MMI)

      • Pronounced meth-IM-a-zole
      • Inhibits the thyroid from using iodine to produce thyroid hormone.
      • Brand name Tapazole (pronounced tap-UH-zole), from Jones Pharma Inc., also generic methimazole
      • Carbimazole -- pronounced car-BIM-a-zole -- which metabolizes to methimazole and is known by its brand name NeoMercazole, is typically used in the UK and Europe.

        PROPYLTHIOURACIL (PTU)

        • Pronounced proe-pill-thye-oh-YOOR-a-sill)
        • PTU inhibits the thyroid from using iodine to produce thyroid hormone, and inhibits T4-to-T3 conversion. Shorter half-life, requires multiple daily dosage, more side effects
        • Only available in generic
        • Less frequently used, due to risks of liver damage


        RECOMBINANT TSH DRUG / THYROTROPIN ALFA

        Recombinant TSH is used for thyroid cancer patients prior to scans for recurrence, to allow for accurate scanning and without having to experience the side effects of hypothyroidism.

        • Also known as recombinant TSH
        • Only brand name: Thyrogen, from Genzyme
        • Given by injection, for thyroid cancer patients preparing to have radioactive iodine after surgery, and preparing for scan to assess recurrence or leftover cancer cells


        THYROID DRUG COMPANIES

        Abbott Laboratories/AbbVie
        100 Abbott Park Rd., Abbott Park, Illinois 60064-3500, (800) 255-5162, http://www.abbott.com, Manufactures: Synthroid (levothyroxine) http://www.synthroid.com

        Actavis/Allergan
        US Corporate HQ website: http://www.actavis.us/en-us/home
        Manufactures: Armour Thyroid (natural desiccated thyroid)
        Armour Thyroid: http://www.armourthyroid.com

        Genzyme Therapeutics
        500 Kendall Street, Cambridge, MA 02142, 800 745 4447, 617 768 9000, http://www.genzyme.com
        Manufactures: Thyrogen (thyrotropin alfa/recombinant TSH)

        Jones Pharma Incorporated, Subsidiary of Pfizer
        501 Fifth Street, Bristol, Tennessee 37620, (888) 840-5370, (800) 776-3637 Fax: (866) 990-0545, http://www.kingpharm.com
        Manufactures: Levoxyl (levothyroxine) Levoxyl -- http://www.levoxyl.com -- 866-LEVOXYL (538-6995), Cytomel (liothyronine), Tapazole (methimazole)

        Lannett Pharmaceuticals
        9000 State Road, Philadelphia, PA 19136, (800) 325-9994, (215) 333-9000, http://www.lannett.com, Manufactures: Unithroid (distributes for manufacturer Jerome Stevens) (levothyroxine)

        RLC Laboratories
        28248 N Tatum Blvd, Ste B1-629, Cave Creek, AZ 85331, 623-879-8537, Fax: 623-879-8683, Toll-free-877.797.7997, http://www.rlclabs.com
        Nature-Throid -- http://www.nature-throid.com
        WP Thyroid - http://www.wpthyroid.com
        Manufactures: WP Thyroid and Nature-Throid

        Akrimax /Tirosint
        11 Commerce Drive, 1st Floor, Cranford, NJ 07016 USA 908-372-0506, http://www.akrimax.com
        Manufactures: Tirosint - http://www.tirosint.com

        Continue Reading