Tylenol After Surgery

How to Use Acetaminophen Safely After Surgery

prescription pill bottle
Taking Tylenol as Prescribed is Key. adam.about.net

What is Tylenol?

Tylenol is a non-narcotic, over the counter medication for the relief of minor to moderate pain, aches, headache and fever.   It can be used for pain related to injuries, is commonly used after surgery, and is effective for reducing a temperature in adults and children.  It is also found in many over the counter combination medications, such as Tylenol PM, which combines Tylenol with Benadryl (diphenhydramine) in order to improve sleep along with reduced pain.

Tylenol is also commonly found in prescription pain medications such as Percocet.  

Other Names For Tylenol

Tylenol is also known as acetaminophen or APAP.  In countries outside the United States this medication is known as paracetamol and by multiple brand names. 

Appropriate Dosing of Tylenol

Tylenol is typically taken every four to six hours, and the dose varies based on age.  For adults, 325-650 milligrams can be taken with each dose.  The maximum recommended dose per day is 3,000-4,000 milligrams.  

The maximum recommended dose is under review, current recommendations are that that healthy individuals may take up to 4,000 milligrams per day.  Individuals with liver disease, who drink alcohol in large or frequent quantities, and individuals with no food intake should not exceed 3,000 milligrams due to the risk of liver damage.

How Tylenol Is Given

Tylenol is available in multiple forms.  Over the counter, the medication is available as a liquid gel capsule, in tablet and liquid form.

  By prescription, the medication can be given as an IV solution or a suppository for rectal administration. 

Pregnancy, Breast Feeding and Tylenol

Tylenol is a category B medication, and is considered safe for use while pregnant and breast feeding.  During pregnancy, IV Tylenol should be avoided when possible, but other forms of Tylenol are considered completely safe at recommended doses.

When breast feeding, a small amount (less than 3%) of the medication can pass to the infant, but this is considered safe unless the infant has a reaction to the Tylenol.  Typically, the reaction is a rash, but in rare cases can be more significant.  For most infants, the Tylenol causes no reaction and can be used safely by the mother. 

Harmful Side Effects of Tylenol

Tylenol is known to cause liver damage and liver failure in those who take too much.  The 3,000-4,000 milligram maximum daily dose is considered safe, but even at those doses liver damage can occur in individuals who have liver problems or drink alcohol excessively.

In the most severe cases, including accidental and intentional overdoses, the liver can fail completely and only a liver transplant can save the individual’s life.  

It is very important to follow the recommended dosing on the packaging.  Exceeding the recommended dosage on a regular basis, or even once if the dose is large enough, can result in a life-threatening illness that may not respond to treatment.


If your pain is not controlled with the standard dose of Tylenol, seek medical treatment for your pain rather than increasing the amount of Tylenol you take. 

Another Warning About Tylenol

Tylenol is found in many medications that are not called Tylenol or acetaminophen.  For example, many cough and cold remedies contain Tylenol.  Prescription pain relievers, such as Vicodin, Norco and Percocet all contain Tylenol.  Many over the counter medications, such as Dayquil, Goody’s Powders, Mucinex, Robitussin, Sudafed and Alka-Seltzer also contain acetaminophen in some of their formulations.  

These medications should be taken carefully with acetaminophen.  Whether the medication comes in a package labeled Tylenol or another brand name, the total dose of Tylenol that is acceptable on a daily basis stays the same.  

Taking a full dose of a medication that contains Tylenol, along with additional Tylenol tablets can result in an overdose of Tylenol.   The same is true of taking “extra” pain medication over and above the amount prescribed.   

Following the prescription/packaging instructions is necessary to avoid taking too much Tylenol. 

Tylenol and Fever After Surgery

Taking Tylenol after surgery can help with mild to moderate surgical pain, and can also deal with the fever commonly present in the days after a procedure.  Keep in mind that Tylenol, taken regularly, can also mask the presence of a fever or infection.  For that reason, be aware of the symptoms of infection other than fever, and inspect your incision daily for any signs of infection.  

Good hand washing and wound care can help prevent most infections, but early diagnosis when an infection does occur can mean the difference between quick and effective treatment and a longer, more difficult recovery. 


Acetaminophen Monograph.  Accessed March, 2016. http://www.drugs.com/monograph/acetaminophen.html

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