Using Vitamins for Age-Related Macular Degeneration

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Macular degeneration (also known as age-related macular degeneration, or AMD) is a disease that gradually wipes out your central vision. Central vision is essential for reading, driving, and other activities that require you to see objects clearly.

A leading cause of vision loss in older Americans, AMD causes deterioration in the macula. The macula is the center of the retina, the light-sensitive tissue responsible for converting images into nerve signals and sending them to your brain.

Vitamins and Supplements for Macular Degeneration

So far, scientific support for the claim that supplements can prevent or treat macular degeneration is limited. 

1) Lutein and Zeaxanthin

A growing number of studies show that these two antioxidants may play a role in reducing the development and progression of AMD. Available in supplement form, lutein and zeaxanthin are found naturally in dark green leafy vegetables, broccoli, Brussels sprouts, and other foods.

2) Ginkgo Biloba

Several small studies suggest that ginkgo biloba (an herb said to stimulate circulation) may help preserve vision in people with AMD.

3) Bilberry

In a 2005 study on rats, researchers found that long-term supplementation with bilberry extract helped prevent AMD (as well as cataracts).

4) Vitamins for Prevention

In the Age-Related Eye Disease Study (a major National Eye Institute-sponsored clinical trial that followed about 3,600 people with varying stages of AMD), researchers found that taking high levels of antioxidants and zinc daily can reduce the risk of developing advanced AMD by about 25 percent.

The study's vitamin formulation consists of:

Tips for Macular Degeneration Prevention

Take these steps to reduce your risk of developing AMD:

  • Get regular eye exams
    • Wear sunglasses when outdoors during daylight hours
    • Exercise regularly

    The Difference Between Dry AMD and Wet AMD

    Dry AMD (the more common form of AMD) occurs when light-sensitive cells in the macula slowly break down, which gradually blurs central vision in the affected eye.

    In wet AMD, abnormal blood vessels grow under the macula and then leak blood or fluid, which rapidly damages the macula.

    Symptoms of Macular Degeneration

    Symptoms of dry AMD may include:

    • Blurred vision
    • A blurred or blind spot in the center of your visual field
    • Difficulty recognizing faces
    • Increasing need for bright light when reading
    • A decrease in the intensity or brightness of colors

    In people with wet AMD, straight lines often appear crooked. People with wet AMD may also experience a small blind spot, which can result in loss of central vision.


    Although the cause of macular degeneration has yet to be determined, the disease is known to develop as the eye ages. People over age 60 are at the greatest risk.

    Other risk factors for AMD include:

    • Smoking
    • Obesity
    • A family history of AMD

    Caucasians and women also appear to have an increased risk for AMD.

    Using Natural Remedies

    Due to the limited research, it's too soon to recommend alternative medicine for macular degeneration.

     It's also important to note that self-treating a condition and avoiding or delaying standard care may have serious consequences. If you're considering using alternative medicine, make sure to consult your physician first.


    Carpentier S, Knaus M, Suh M. "Associations between lutein, zeaxanthin, and age-related macular degeneration: an overview." Crit Rev Food Sci Nutr. 2009 49(4):313-26.

    Coleman H, Chew E. "Nutritional supplementation in age-related macular degeneration." Curr Opin Ophthalmol. 2007 18(3):220-3.

    Evans JR. "Ginkgo biloba extract for age-related macular degeneration." Cochrane Database Syst Rev. 2000;(2):CD001775.

    Fies P, Dienel A. "Ginkgo extract in impaired vision--treatment with special extract EGb 761 of impaired vision due to dry senile macular degeneration." Wien Med Wochenschr. 2002;152(15-16):423-6.

    Fursova AZh, Gesarevich OG, Gonchar AM, Trofimova NA, Kolosova NG. "Dietary supplementation with bilberry extract prevents macular degeneration and cataracts in senesce-accelerated OXYS rats." Adv Gerontol. 2005;16:76-9.

    Disclaimer: The information contained on this site is intended for educational purposes only and is not a substitute for advice, diagnosis or treatment by a licensed physician. It is not meant to cover all possible precautions, drug interactions, circumstances or adverse effects. You should seek prompt medical care for any health issues and consult your doctor before using alternative medicine or making a change to your regimen.