What is a Halo Nevus?

Moles with Halos

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Halo Nevus - Halo Moles

A halo nevus is a mole that is surrounded by round, symmetric depigmented area or a halo. The halo itself has sharply demarcated borders. There are no melanocytes or cells that make melanin, in the halo area. Halo nevi develop spontaneously, usually in adolescence, on the trunk, but sometimes on the palms and soles. A person can have just one halo nevus or several halo nevi.

Halo nevi are usually benign. No treatment is done if they have a typical appearance, other than reassuring the patient that they are not a concern for skin cancer. The white skin around a halo nevis may be more prone to sunburn, so the use of sunscreen is a good idea to protect the skin. Halo nevi often disappear on their own, but it can take ten years or more.

  • Plural: halo nevi, halo naevi
  • Alternate Names: halo naevus, halo moles, Grünewald nevus, Sutton naevus, leukoderma acquisita centrifugum, Perinevoid vitiligo
  • Pronunciation: HAY-loh NEE-vus • (noun)

Who Has Halo Nevi?

About 1% of people in the United States have halo nevi. It occurs across all racial groups and genders. It is often found in children. The incidence of vitiligo may be increased in people who have halo nevi. 

What is the Typical Development of a Halo Nevus?

The usual progression of development of a halo nevus is that a lighter ring develops around a mole.

The mole itself may then become lighter in color and even fade away, leaving only the depigmented circular area. Eventually, over the course of years, the skin regains its usual color in the area.

What Causes a Halo Nevus?

A halo nevus appears when the body has an immune response around an existing mole.

Why this happens continues to be studied. Immune cells come into the area around the nevus cells and clear out any melanocytes, leaving the area unpigmented. The cells involved are usually T-lymphocytes and some macrophages. Antibodies to melanoma cells have been found in people with halo nevi, but it isn't clear whether the antibodies led to the removal of the melanocytes around the mole or whether they formed after the mole cells were disrupted.

Is it Skin Cancer?

Melanoma can rarely occur in a halo nevus, but in those cases, the nevus has atypical features and the depigmented ring is not symmetric. A doctor will check any halo nevus during a skin exam for features that make it suspicious for melanoma, basal cell carcinoma and other conditions that may require treatment.

Generally, a halo nevus does not have to be removed unless it has atypical features. Removing the nevus does not cause the halo portion to get darker. For this reason, removal can cause a noticeable scar in an area of lighter skin color.

History of Halo Nevus

This is a case where art has one of the earliest accurate depictions of a skin lesion, appearing in "The Temptation of St. Anthony," bt Matthias Grünewald, a nightmarish painting that is part of the Isenheim Altarpiece, created from 1512-1516. The lesion was named leukoderma acquisita centrifugum by Sutton in 1916.


Zeff RA, Freitag A, Grin CM, Grant-Kels JM. The immune response in halo nevi. J Am Acad Dermatol. 1997 Oct. 37(4):620-4.

Aouthmany M, Weinstein M, Zirwas MJ, et al; The natural history of halo nevi: a retrospective case series. J Am Acad Dermatol. 2012 Oct;67(4):582-6. doi: 10.1016/j.jaad.2011.11.937. Epub 2012 Mar 2.

Zabawski Jr E et al; Halo Nevus, Medscape, Apr 2014

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