What Is Sleep-Related Laryngospasm?

Causes Include Sleep Apnea, Heartburn, and Postnasal Drip

A man treats his sleep apnea, a possible cause of sleep-related laryngospasm
A man treats his sleep apnea, a possible cause of sleep-related laryngospasm. Science Picture Co/Getty Images

If you have ever awakened choking out of sleep, you no doubt wondered about the potential cause. It can be a scary occurrence with several possible triggers. Learn about one, sleep-related laryngospasm, and how it might relate to other problems including sleep apnea and nocturnal heartburn. By discovering the trigger, hopefully you can find the proper treatment to prevent a future recurrence.

What Causes Choking in Sleep?

There are several potential causes of choking, gasping, or coughing out of sleep.

Most commonly, this occurs as part of obstructive sleep apnea. When the soft tissues of the throat collapse into the airway, it is necessary to wake suddenly to resume normal breathing. This most often occurs when the soft palate, uvula, and tongue block the throat. However, other potential structures can block airflow into the lungs and lead to an awakening.

Sleep-related laryngospasm occurs when the muscles and soft tissues surrounding the trachea (or windpipe) contract or swell and narrow the passage. This may cause noisy breathing similar to snoring, but it is characterized by a high-pitched and strained inspiratory sound called stridor. It seems to occur more often during REM sleep.

When the airflow is sufficiently interrupted, sometimes completely, an awakening is triggered by the brain. This leads to a sudden arousal from sleep. The blockage may last from 5 to 45 seconds prior to the awakening.

However, the noisy stridor may persist for several minutes after waking. Eventually the breathing returns to normal.

There may be a sensation of chest pain or heartburn. It may be associated with a sense of suffocation and this may lead to feelings of panic and fear. In rare cases, the person may appear blue (with cyanosis).

The rate of breathing may be increased to greater than 20 breaths per minute (tachypnea). The discomfort and panic may contribute to fear of falling asleep and insomnia.

What Common Conditions Are Associated with Sleep-Related Laryngospasm?

As noted, obstructive sleep apnea may commonly be mistaken for and associated with sleep-related laryngospam. There are other associated symptoms. Individuals with typical sleep apnea will not usually wake with persistent difficulty breathing or stridor once awake.

Nocturnal heartburn or gastro-esophageal reflux disease (GERD) at night may contribute to the laryngospasm. When acid enters the lower esophagus and trachea, it may cause swelling. Most people will also experience GERD during the daytime.

It may be triggered by the use of sleeping pills called hypnotics or by other medications that affect breathing by suppressing the central nervous system (brainstem) or by relaxing the muscles of the airway. In addition, it seems that postnasal drip that may occur with chronic allergies may be a trigger in some.

What Rare Conditions Are Associated with Sleep-Related Laryngospasm?

Less often it may be a manifestation of sleep terrors. These usually affect children, but may persist into adulthood, and are often associated with impaired breathing, choking, a rapid heartbeat, and agitation. Abrupt awakenings, difficulty breathing, and a fear of dying are also seen in panic disorder, though episodes would also occur during the daytime. Asthma at night may cause coughing, wheezing, and shortness of breath in sleep. REM behavior disorder, in which a person wakes acting a dream, can also be a possibility.

What else could it be? There are a few other rare causes of sleep-related laryngospasm. Seizures may occur in children and lead to similar symptoms. Tumors within the airway may be a cause and endoscopy can identify any potential dysfunction of the vocal cords or other pathology. In adults, a progressive neurological disease called multiple system atrophy is often associated with stridor.

If you are concerned that you may be suffering from episodes of laryngospasm during sleep, speak with your doctor about your symptoms to determine the most likely cause. It may be necessary to have a diagnostic sleep study called a polysomnogram. Further testing can be arranged and sometimes empiric trials of medications for heartburn can be helpful.


American Academy of Sleep Medicine. International classification of sleep disorders, 3rd ed. Darien, IL: American Academy of Sleep Medicine, 2014.

Roland MM, et al. “Sleep related laryngospasm caused by gastroesophageal reflux.” Sleep Med. 2008;9:451-3.

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